{"id":6377,"date":"2024-09-05T13:30:58","date_gmt":"2024-09-05T10:30:58","guid":{"rendered":"https:\/\/avrupacerrahi.net\/en\/?p=6377"},"modified":"2024-10-03T15:53:40","modified_gmt":"2024-10-03T12:53:40","slug":"is-hidradenitis-suppurativa-genetic-causes-and-risk-factors","status":"publish","type":"post","link":"https:\/\/avrupacerrahi.net\/en\/is-hidradenitis-suppurativa-genetic-causes-and-risk-factors\/","title":{"rendered":"Is Hidradenitis Suppurativa Genetic? Causes and Risk Factors"},"content":{"rendered":"<p><b><a href=\"https:\/\/avrupacerrahi.net\/en\/hidradenitis-suppurativa\/\">Hidradenitis suppurativa<\/a><\/b> (HS) is a chronic skin condition that forms painful nodules and abscesses under the skin. This condition causes inflammation and the formation of fistulas on the surface of the skin. But is hidradenitis suppurativa a genetic disease? In this article, we will examine whether the disease is genetic and the risk factors.<\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_80 ez-toc-wrap-left counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/avrupacerrahi.net\/en\/is-hidradenitis-suppurativa-genetic-causes-and-risk-factors\/#Is_Hidradenitis_Suppurativa_Genetic\" >Is Hidradenitis Suppurativa Genetic?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/avrupacerrahi.net\/en\/is-hidradenitis-suppurativa-genetic-causes-and-risk-factors\/#Family_Background_and_Genetic_Predisposition\" >Family Background and Genetic Predisposition<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/avrupacerrahi.net\/en\/is-hidradenitis-suppurativa-genetic-causes-and-risk-factors\/#Genetic_Mutations\" >Genetic Mutations<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/avrupacerrahi.net\/en\/is-hidradenitis-suppurativa-genetic-causes-and-risk-factors\/#Non-Genetic_Risk_Factors_of_Hidradenitis_Suppurativa\" >Non-Genetic Risk Factors of Hidradenitis Suppurativa<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/avrupacerrahi.net\/en\/is-hidradenitis-suppurativa-genetic-causes-and-risk-factors\/#Smoking\" >Smoking<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/avrupacerrahi.net\/en\/is-hidradenitis-suppurativa-genetic-causes-and-risk-factors\/#Obesity\" >Obesity<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/avrupacerrahi.net\/en\/is-hidradenitis-suppurativa-genetic-causes-and-risk-factors\/#What_should_be_done_in_case_of_genetic_predisposition\" >What should be done in case of genetic predisposition?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/avrupacerrahi.net\/en\/is-hidradenitis-suppurativa-genetic-causes-and-risk-factors\/#Early_Diagnosis_and_Treatment_Options\" >Early Diagnosis and Treatment Options<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n\n<div id=\"attachment_6379\" style=\"width: 860px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-6379\" class=\"size-full wp-image-6379\" src=\"https:\/\/avrupacerrahi.net\/en\/wp-content\/uploads\/2024\/09\/Hidradenitis-Suppurativa-HS-1.png\" alt=\"Hidradenitis Suppurativa \" width=\"850\" height=\"500\" srcset=\"https:\/\/avrupacerrahi.net\/en\/wp-content\/uploads\/2024\/09\/Hidradenitis-Suppurativa-HS-1.png 850w, https:\/\/avrupacerrahi.net\/en\/wp-content\/uploads\/2024\/09\/Hidradenitis-Suppurativa-HS-1-300x176.png 300w, https:\/\/avrupacerrahi.net\/en\/wp-content\/uploads\/2024\/09\/Hidradenitis-Suppurativa-HS-1-768x452.png 768w\" sizes=\"auto, (max-width: 850px) 100vw, 850px\" \/><p id=\"caption-attachment-6379\" class=\"wp-caption-text\">Hidradenitis Suppurativa<\/p><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Is_Hidradenitis_Suppurativa_Genetic\"><\/span><strong>Is Hidradenitis Suppurativa Genetic?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><strong>Hidradenitis Suppurativa<\/strong>may be associated with a genetic predisposition. Research shows that the disease can be influenced by genetic factors and that people with a family history of the disease have a higher risk. However, this factor alone is not enough to say that hidradenitis suppurativa is genetic; environmental factors and lifestyle also play a big role.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Family_Background_and_Genetic_Predisposition\"><\/span><strong>Family Background and Genetic Predisposition<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Approximately 30% of individuals with hidradenitis suppurativa have a family member with the same disease. This indicates that the disease may be associated with a genetic predisposition. People with a family history of the disease may be at higher risk of developing hidradenitis suppurativa.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Genetic_Mutations\"><\/span><strong>Genetic Mutations<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Some research suggests that hidradenitis suppurativa may be linked to genetic mutations. Mutations in genes such as NCSTN, PSEN1, and PSENEN may play a role in the development of the disease. These genes are important for the normal functioning of skin cells and the immune system.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Non-Genetic_Risk_Factors_of_Hidradenitis_Suppurativa\"><\/span><strong>Non-Genetic Risk Factors of Hidradenitis Suppurativa<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Apart from genetic predisposition, the disease has many other risk factors. These factors can increase the possibility of the disease occurring and worsen symptoms.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Smoking\"><\/span><strong>Smoking<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Smoking is one of the most common triggers of hidradenitis suppurativa. Smoking can exacerbate the disease by increasing skin inflammation. Smoking can also negatively affect the response to treatment.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Obesity\"><\/span><strong>Obesity<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Obesity is a major risk factor in the development of hidradenitis suppurativa. Excess weight can cause friction and irritation of the skin, which increases the risk of inflammation. Weight control can play a critical role in managing the disease.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_should_be_done_in_case_of_genetic_predisposition\"><\/span><strong>What should be done in case of genetic predisposition?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>People with a family history of <a href=\"https:\/\/en.wikipedia.org\/wiki\/Hidradenitis\">hidradenitis suppurativa<\/a> should be more alert to symptoms. Early diagnosis is crucial to slow the progression of the disease and evaluate treatment options. Regular dermatologist check-ups are recommended for individuals with a genetic predisposition.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Early_Diagnosis_and_Treatment_Options\"><\/span><strong>Early Diagnosis and Treatment Options<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Early detection is critical to prevent disease progression and minimize damage to the skin. At <a href=\"https:\/\/avrupacerrahi.net\/en\/\">Avrupa Cerrahi\u00a0 Proctology Center<\/a>, we offer modern methods and personalized treatment plans for the treatment of hidradenitis suppurativa. If you have a genetic predisposition, contact our specialists for early diagnosis and treatment options.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hidradenitis suppurativa (HS) is a chronic skin condition that forms painful nodules and abscesses under the skin. This condition causes inflammation and the formation of fistulas on the surface of the skin. But is hidradenitis suppurativa a genetic disease? In this article, we will examine whether the disease is genetic and the risk factors. Is<\/p>\n","protected":false},"author":2,"featured_media":6534,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"content-type":"","footnotes":""},"categories":[61],"tags":[83,62,86,87,85,84],"class_list":["post-6377","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hidradenitis-suppurativa","tag-early-diagnosis-and-treatment-options","tag-hidradenitis-suppurativa","tag-is-hidradenitis-suppurativa-genetic","tag-is-hidradenitis-suppurativa-genetic-causes-and-risk-factors","tag-non-genetic-risk-factors-of-hidradenitis-suppurativa","tag-what-should-be-done-in-case-of-genetic-predisposition"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/avrupacerrahi.net\/en\/wp-json\/wp\/v2\/posts\/6377","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/avrupacerrahi.net\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/avrupacerrahi.net\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/avrupacerrahi.net\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/avrupacerrahi.net\/en\/wp-json\/wp\/v2\/comments?post=6377"}],"version-history":[{"count":2,"href":"https:\/\/avrupacerrahi.net\/en\/wp-json\/wp\/v2\/posts\/6377\/revisions"}],"predecessor-version":[{"id":6380,"href":"https:\/\/avrupacerrahi.net\/en\/wp-json\/wp\/v2\/posts\/6377\/revisions\/6380"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/avrupacerrahi.net\/en\/wp-json\/wp\/v2\/media\/6534"}],"wp:attachment":[{"href":"https:\/\/avrupacerrahi.net\/en\/wp-json\/wp\/v2\/media?parent=6377"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/avrupacerrahi.net\/en\/wp-json\/wp\/v2\/categories?post=6377"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/avrupacerrahi.net\/en\/wp-json\/wp\/v2\/tags?post=6377"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}